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The symbiotic relationship between phenolic compounds and gut microbiota have gained attention due to their relevance in supporting human health, specifically in their role for gut & digestive support as well as skin health and beauty from within. In particular, pomegranate has long been associated with possessing high content antioxidant polyphenols, in particular ellagitannins such as punicalagins and their gut-derived metabolites, urolithins.
Overall, findings from pre-clinical and human clinical studies support pomegranate ellagitannins, namely punicalagins, can: