Tinospora cordifolia promotes balanced immune response through histamine modulation

The immune system is a complex system comprised of the innate and adaptive systems which impact immune health responses from two, broadly different ways. Commonly, in response to histamine, immune responses include symptoms of nasal congestion, sneezing, and/or itchy red, watery eyes. Historically, Tinospora has been used to promote a balanced and optimal immune response through polysaccharides and polyphenols and recently, reviewers have evaluated the immunomodulatory potential of Tinospora cordifolia.

Recently, researchers reviewed the immune health attributes of Tinospora. They explain that “Polymorphonuclear leukocytes (PMNs) are immune cells that possess small granules filled with enzymes (e.g. myeloperoxidase and lysozyme) and molecules (e.g. superoxide and histamine) that are released during infections, allergic reactions, and [offer respiratory support]. The PMN family includes neutrophils, eosinophils, mast cells, and basophils.”⁵ These cells, in addition to their defense mechanisms, devour the foreign pathogens and bacteria.⁵

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